How to Increase Titers with Gibco FunctionMAX Titer Enhancer

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How to improve titers if you have a drop-off in specific productivity late in a high-density fed-batch culture. Gibco FunctionMAX Titer Enhancer can achieve up to double titer while reducing cost per gram of protein. You can increase specific productivity without increasing cell density. Minimal optimization is required. FunctionMAX is a titer enhancer that can be added to current process or as a partial feed replacement. It can reduce process development time with less regulatory compliance risk. This is a highly concentrated, pH-neutral additive for CHO fed-batch processes. It has no impact on bioreactor pH and helps reduce product quality risk. If you have an extremely low peak cell density fed-batch culture, consult with Gibco Bioproduction Services for advice on cell adaptation and/or fed-batch optimization. If you have no drop-off in specific productivity late in a high-density fed-batch culture, consult with Gibco Bioproduction Services for advice on fed-batch optimization for increasing titers. For more information, visit https://www.thermofisher.com/us/en/home/life-science/bioproduction/gibco-bioprocessing/functional-additives/functionmax-titerenhancer.html

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